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Intra-abdominal Hypertension in Critically Ill Patients

Intra-abdominal Hypertension in Critically Ill Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02514135
Enrollment
286
Registered
2015-08-03
Start date
2015-09-01
Completion date
2016-05-30
Last updated
2018-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal Compartment Syndrome, Intra-Abdominal Hypertension

Brief summary

The aim of the proposed study is to determine the incidence and prevalence of intra-abdominal hypertension and abdominal compartment syndrome in consecutive intensive care admissions using broad inclusion criteria.

Detailed description

Increased pressure within the abdominal cavity is particularly common in intensive care patients and has been shown to be an independent risk-factor for mortality in this patient population. The quoted rates of intra-abdominal hypertension of range anywhere from 20-60% are dependent on the population of patient studied. The prospective observational studies performed to date have been underpowered, used strict inclusion/exclusion criteria or were performed prior to consensus guidelines on the definition and measurement of intra-abdominal pressure and hypertension.

Interventions

OTHERNo intervention

Sponsors

Western University, Canada
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Foley catheter in-situ on admission

Exclusion criteria

* Contra-indication to bladder pressure measurement * Home service asked that patient is not included * Death within 24 priors of admission before bladder pressure measured * No bladder pressure performed within 24 hours of admission * Consent refused or unable to be obtained (lack of SDM, patient unable to provide)

Design outcomes

Primary

MeasureTime frameDescription
MortalityWhile patient in-hospital, expected stay one week on averageAs measured prospectively by patient death in the ICU

Secondary

MeasureTime frameDescription
Length of stayWhile patient in-hospital, expected stay one week on averageMeasured prospectively from date of admission to ICU to death, or discharge from ICU
Abdominal decompressionWhile patient in-hospital, expected stay one week on averageMidline laparotomy for abdominal compartment syndrome

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026