Allergy to Tree Pollen
Conditions
Keywords
Allergy to Cupressus pollen
Brief summary
Biological Standardization of Cupressus arizonica Allergen Extract.
Detailed description
This is an open, unblinded and non-randomized biological assay. The study design is a slight modification of the recommendations proposed by the Nordic Guidelines.
Interventions
BIOLOGICALCupressus arizonica
Four different concentrations of Cupressus arizonica allergen extract, positive control and negative control
Sponsors
Laboratorios Leti, S.L.
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Subject has provided written informed consent, appropriately signed and dated by subject. * Subject can be male or female of any race and ethinic group. * Age 18 years and 60 years ata the study inclusión day. * Positive clinical history of inhalatory allergy to Cupressus arizonica. * A positive prick test with a standarices commercially Cupressus arizonica allergen extract. * A positive prick test with positive control of histamine 10 mg/ml. * A positive test for specific IgE to Cupressus arizonica.
Exclusion criteria
* Immunotherapy in the past 5 years with an allergen extract Cupressus arizonca or other allergen extract than may interfere with the allergene to be tested. * Use of drugs that may interfere before and after with the skin reactions. * Treatment with certain drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wheal size area (mm2) on the skin at the site of the puncture during the inmediate phase | Test sites should be inspected and recorded 15-20 min after application |
Countries
Spain
Outcome results
None listed