Hypertension
Conditions
Brief summary
This is a study of women aged 18-65, to determine the physiological effects of consuming burdock root in supplement form. Burdock has long been used by herbalists for its diuretic and blood sugar lowering properties.
Detailed description
This study will allow us to determine the effect of burdock consumption on basic laboratory tests such as the complete metabolic panel (CMP) as well as the effect on blood pressure over time. Participants will self-monitor their blood pressures and undergo lab testing. They will also complete symptom inventories to determine subjective factors that change with burdock consumption, such as menstrual water retention. Subjects will undergo electronic body composition testing before and after the intervention.
Interventions
DIETARY_SUPPLEMENTBurdock
Subjects will consume burdock daily and will undergo laboratory tests to determine the effect of burdock, if any, on organ function.
DIETARY_SUPPLEMENTPlacebo
Methylcellulose (inert) tablet taken as placebo
Sponsors
Proactive Health Labs
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
21 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Must be able to swallow tablets * African-American race * Able to travel to our clinic in Santa Monica
Exclusion criteria
* Severely low blood pressure * Hypoglycemia * Baseline creatinine over 1.2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure | 6 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Extracellular/Total Body Water Ratio | 6 Weeks |
| Hemoglobin A1c | 6 weeks |
| Blood urea nitrogen | 6 weeks |
| Body fat percentage | 6 Weeks |
| Fasting Blood Glucose | 6 weeks |
| Liver function tests | 6 weeks |
| Creatinine | 6 weeks |
Contacts
Primary ContactDr De
Outcome results
None listed