Breast Neoplasms
Conditions
Brief summary
Excessive sitting time (sedentary time) has been associated with risk of insulin resistance and other factors which may be relevant to breast cancer prognosis. This 8-week study tests different strategies for helping breast cancer survivors to modify their levels of sitting time. Participants will be assigned with equal likelihood to one of three groups (1) overall reduction in sitting time, (2) interruption of sitting time with standing breaks, and (3) usual care.
Interventions
BEHAVIORALRe-Patterning Sitting Time Group
This is a behavioral intervention to help women interrupt long bouts of sitting time by incorporating standing breaks into their lifestyle.
BEHAVIORALReducing Sitting Time Group
This is a behavioral intervention to help women reduce their overall accumulated sitting time by 2 hours per day.
BEHAVIORALUsual Care
This intervention consists solely of follow-up contact to control for attention effects and reduce attrition.
Sponsors
University of Wisconsin, Madison
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
1. diagnosed with Stage 0-III breast cancer. Bilateral or multiple primary breast cancers are permitted. 2. Completed primary treatment defined as definitive surgery, (neo)adjuvant chemotherapy and/or (neo)adjuvant radiation. Participants still receiving adjuvant endocrine or HER2 targeted therapies are eligible. 3. Report sitting for ≥8 accumulated waking hours on a typical day, 4. Willing and able to attend 3 study visits at the UW, 5. Willing to attempt reduction of sitting time, 6. Use the internet on a regular basis, 7. Willing and able to complete study requirements, and 8. Currently considered postmenopausal (no menstrual periods in past 12 months), even if pre-menopausal at diagnosis.
Exclusion criteria
1. Evidence of recurrence or metastatic disease, 2. Unable to move from sitting to standing without difficulty and to walk 1 block.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Feasibility as measured by recruitment and retention rates | 12 months | Feasibility of recruiting participants to the study |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sedentary behavior as measured by ActivPal | 7 days | Sedentary time as measured by the ActivPAL inclinometer |
| Physical activity as measured by ActiGraph | 7 days | Physical activity as measured by the ActiGraph accelerometer |
| Sedentary time as measured by ActiGraph | 7 days | Sedentary time as measured by the ActiGraph accelerometer |
Countries
United States
Outcome results
None listed