Obesity
Conditions
Keywords
obesity, nutrition, intervention, food replacement, IOT
Brief summary
This research is aimed at verifying the effects of diets with high protein and low glycemic index (GI) on weight management among overweight or obese Chinese adult. Additionally, the investigators intend to verify the effects of two new approaches, including food replacement and Internet-of-things (IOT) monitoring on weight control.
Interventions
BEHAVIORALEducation
DIETARY_SUPPLEMENTFood replacement
BEHAVIORALIOT monitoring
Sponsors
Chinese PLA General Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Health adult, age:18-65，BMI（kg/m2）:27.0-40.0
Exclusion criteria
* Patients under regular medical treatment for chronic diseases like diabetes, hypertension, gout and hyperuricemia. * The patients with chronic renal diseases or other diseases which impose restrictions on the intake of proteins. * Mental patients. * People who suffer from secondary obesity caused by endocrine, metabolic disorders or some central nervous system diseases. * People who are under medical or surgical weight-loss treatments in the past three months. * People whose weight fluctuations are not less than 5kg in the past two months； * People with food allergies. * Men or women who drink regularly over 25g or 15 g daily,respectively. * Pregnant women and women who prepare to be pregnant. * Lactating women
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Composite changes of weight, waist circumference and BMI | 3~5 years | the measure is a composite |
| Body composition change is measured by means of Bioelectrical Impedance Analysis (BIA) and CT scan | 3~5 years | — |
| Dropout ratio during weight-loss period and maintenance period | 3~5 years | — |
Secondary
| Measure | Time frame |
|---|---|
| Composite changes in cardiovascular health indicators such as blood pressure, blood glucose, and blood lipids | 3~5 years |
| Composite changes in inflammatory markers, diet and physical activity level, Leptin and adiponectin, compliance of weight-loss and other indicators | 3~5 years |
| Composite changes in diet-related behaviors such as satiety, food preferences, social support, appetite, healthy lifestyle and psychological aspects | 3~5 years |
Countries
China
Contacts
Primary ContactYuan He, MD
Outcome results
None listed