Stroke
Conditions
Keywords
locomotion
Brief summary
The overall objective of this subproject is to evaluate the individual and paired contributions of intensity and variability of stepping training on lower extremity (LE) function, health and community participation in patients with chronic hemiparesis post-stroke.
Detailed description
The overall objective of this subproject is to evaluate the individual and paired contributions of intensity and variability of stepping training on lower extremity (LE) function, health and community participation in patients with chronic hemiparesis post-stroke. Using a RCT design/Intervention Efficacy paradigm, Aim 1 will investigate the independent and combined (paired) contributions of intensity and variability of stepping training on locomotor function, with secondary measures of health and community mobility. For Aim 2, we will evaluate the independent and combined effects of intensity and variability of stepping training on non-walking LE tasks. In Aim 3, we will evaluate the cost effectiveness of providing these interventions to accelerate motor recovery and health. Our central hypothesis is that results of this study will provide a theoretical foundation for implementation of physical therapy interventions which can facilitate short-term gains in locomotor function, and contribute to long-term improvements in health, function and participation through increased community mobility.
Interventions
BEHAVIORALexercise
Variable conditions of stepping practice
Sponsors
Shirley Ryan AbilityLab
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Intervention model description
3 arm RCT - high intensity variable, high intensity forward, low intensity variable
Eligibility
Sex/Gender
ALL
Age
30 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* history unilateral stroke \> 6 months duration * walks without physical assistance at speeds \< 1.0 m/s
Exclusion criteria
* no other cardiopulmonary, metabolic, neurological orthopedic injury that may contribute to walking outcomes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in peak walking speed | At baseline, following 8 weeks of training and a 2 month follow-up | fastest comfortable walking speed overground |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Functional Gait Assessment | At baseline, following 8 weeks of training and a 2 month follow-up | dynamic balance activities |
| Change in 5X sit-to-stand transfer time | At baseline, following 8 weeks of training and a 2 month follow-up | non-walking functional mobility task |
Countries
United States
Outcome results
None listed