Comparison of Diclofenac vs. Nepafenac Ophthalmic Drops: Patient Comfort

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02506348

Enrollment

Registered

2015-07-23

Start date

2015-07-31

Completion date

Unknown

Last updated

2015-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Surgical Management, Pain Management, Inflamation Management

Brief summary

In this study we test Diclofenac and Nepafenac and compared patients experience and comfort following administration of these ophthalmic drops.

Detailed description

In this study we will compare the ocular tolerability between preservative-free Diclofenac and Nepafenac drops. Using a standard comparative scale we will measured discomfort, itching, burning and pain in intervals of 1 sec, 5 sec, 1 min and 5 min post-administration. The results may aid both doctors and patients in decision regarding the post surgical anti-inflammatory treatment.

Interventions

DRUGDiclofenac

DRUGNepafenac

Study design

Allocation

Intervention model

SINGLE_GROUP

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patient facing cataract surgery

Exclusion criteria

* under 18 * cognitive decline

Design outcomes

Primary

Measure	Time frame	Description
patient's comfort	1 min post administration	change in patient's comfort between both eyes at 1 min post administration

Secondary

Measure	Time frame	Description
patient's comfort	5 min post administration	change in patient's comfort between both eyes at 10 min post administration

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026