Optimizing Meal and Snack Timing to Promote Health

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02506218

Acronym

S43

Enrollment

Registered

2015-07-23

Start date

2015-04-30

Completion date

2016-03-31

Last updated

2018-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dietary Modification

Brief summary

This study will be conducted using standardized techniques to collect blood samples via an acute, randomized, cross-over design. Subjects will be provided all of their meals the day prior to testing and participate in 3 testing days with a minimum of 1 week break between testing days and a maximum time commitment of 7 weeks. A trained phlebotomist will place a catheter and collect blood samples from an antecubital vein using sterile techniques.

Interventions

DIETARY_SUPPLEMENT10 + 20 g protein consumption

whey isolate

OTHER30 g protein breakfast

30 g mixed meal breakfast

OTHER10 g protein breakfast

10 g mixed meal breakfast

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

25 Years to 39 Years

Healthy volunteers

Yes

Inclusion criteria

25-39 years old * BMI between 22-37 kg/m2 * Weight stable (± 4.5 kg) for the previous 3 months * Not currently (or within the past 6 months) following a vigorous exercise regimen or weight loss program * No acute illness * Not smoking * Not diabetic * Not pregnant or planning pregnancy in the next 3 months * Lactose tolerant * Willing to limit purposeful activity for 48 hours prior to each testing day * Willing to consume study foods and beverages.

Exclusion criteria

* \<25 or \>39 years old, BMI \<22 or \>37 kg/m2 * Currently (or within the past 6 months) following a vigorous exercise regimen greater than -3 - 45 minute exercise sessions per week * Currently following a weight loss program where subject has lost greater than 4.5 kg * Acute illness * Smoking * Diabetic * Pregnant or planning pregnancy in the next 3 months * Lactose intolerant * Unwilling to consume study foods and beverages * Peri and post-menopausal women.

Design outcomes

Primary

Measure	Time frame	Description
Plasma amino acid concentration	7 weeks	Peak plasma concentration of amino acids

Secondary

Measure	Time frame	Description
Blood glucose concentration	7 weeks	Area under the curve of blood glucose

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026