Hypokinetic Dysathria
Conditions
Brief summary
A handful of studies have examined the effects of the Lee Silverman Voice Treatment (LSVT) LOUD on hypokinetic dysarthria in English speakers with Parkinson's disease (PD). Although LSVT LOUD has been found to be effective on improving these speaker's vocal intensity and increasing their speech intelligibility as well as speech function with Phase I evidence, no study has investigated whether Mandarin-speaking individuals with dysarthria secondary to PD would benefit from LSVT LOUD. In the proposed study, speech data of Mandarin-speaking individuals with hypokinetic dysarthria before and after speech therapy will be audio recorded and analyzed in order to examine the effects of LSVT LOUD on the speech function in this population. The same speech data will be played to Mandarin listeners in order to investigate the speech intelligibility of this population. It is hypothesized that Mandarin-speaking individuals with hypokinetic dysarthria secondary to PD will demonstrate reduced vocal intensity, reduced speech intelligibility and impaired speech function before they receive LSVT LOUD. They will improve these speech characteristics following speech therapy and will present with short-term maintenance effects.
Interventions
BEHAVIORALLee Silverman Voice Treatment (SVLT) LOUD
Sponsors
National Taiwan University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
30 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Mandarin-speaking Taiwanese 2. Hypokinetic dysarthria due to Parkinson's disease 3. No other neurodegenerative diseases 4. No cognitive deficits 5. Age range 30 years and above
Exclusion criteria
1. Not able to follow verbal directions, 2. speech characteristics uncommon to Parkinson's disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Speech intelligibility | Immediate | Speech intelligibility will be assessed by native Mandarin listeners' orthographic transcription accuracy and ratings based on a nine-point Likert scale (from 1 - very difficult to understand to 9 - very easy to understand). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Speech function | Immdediate | Speech function will be assessed using acoustic methods. E.g., vowel formant frequencies correlated with vowel articulation will be extracted and analyzed using Praat software. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Quality of life measured by PDQ-39 | Immediate | This area of assessment will be measured by Parkinson's Disease Questionnaire (PDQ-39) (Jenkinson, Fitzpatrick, Peto, Greenhall, & Hyman, 1997). This battery provides information on areas that affect participants' well-being and the degree affected. |
| Depression level measured by BDI-II | Immediate | Some patients with PD develop depression that affects their daily life. Therefore, it is necessary to assess their depression level with Beck Depression Inventory-II (Beck, Steer, & Brown, 1996) |
| Cognitive status measured by MMSE | Immediate | It is necessary to assess their cognitive status with Mini-mental State Examination (MMSE) (Folstein, Foistein, & McHugh, 1975) and the score will be used as the inclusion or exclusion criteria. |
Countries
Taiwan
Contacts
Primary ContactRuei-Meei Wu
Backup ContactWen-Chieh Yang
Outcome results
None listed