Hyperplasia
Conditions
Brief summary
Hyperplasia of Mammary Glands is a complex disease, and there is no consensus or guideline for the treatment of this disease. This study was launched to investigate into the problem that which patients should be diagnosed as hyperplasia of mammary glands and which patients should be treated.
Detailed description
Females who meet the inclusion criteria will receive breast ultrasonography, mammography and pathological examinations by core needle biopsy. All participants will receive a follow-up at an 6-month interval for 2 years. During the follow-up period, whether the symptoms relieve will be evaluated.
Interventions
OTHERNo intervention
Sponsors
Shandong University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
25 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Reported breast pain or breast lumps. * Willing to be kept follow-up. * Functions below are maintained in major organs: liver, renal and heart. * Written informed consent will be obtained for patients for entering this study.
Exclusion criteria
* Typical breast cancer or fibroadenoma. * Classification by breast ultrasonography of mammography is beyond Breast Imaging - Reporting And Data System (BI-RADS) 4. * Oral contraceptive or hormone replacement therapy. * History of breast cancer or other malignancies. * History of pituitary gland disease. * Potentially pregnant, pregnant, or breast-feeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical manifestations as an substitutive indicator for pathological diagnosis of hyperplasia of mammary glands | 8 months |
Secondary
| Measure | Time frame |
|---|---|
| Clinical manifestations as an surgical indications for hyperplasia of mammary glands | 8 months |
Countries
China
Contacts
Primary ContactGang Z Yu, PhD, MD
Outcome results
None listed