Physiological and Clinical Changes in NHF Therapy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02504814

Acronym

ATMOFLOW

Enrollment

Registered

2015-07-22

Start date

2011-06-30

Completion date

2018-06-30

Last updated

2019-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease, Hypercapnia, Interstitital Lung Disease

Keywords

nasal high flow

Brief summary

The study explores the changes in pressure, volume and in hypercapnia in patients with COPD and ILD. The investigators will use different application forms.

Interventions

DEVICENasal Highflow (NHF)

changes in breathing physiology in NHF

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* COPD, ILD

Exclusion criteria

* Unstable disease

Design outcomes

Primary

Measure	Time frame
changes in mean airway pressure (mbar)	1 month
changes in tidal and minute volume (l)	1 month
changes in breathing frequency (beats/ minute)	1 month

Secondary

Measure	Time frame
changes in partial pressure of carbon dioxide (CO2) in arterial blood (pCO2)	4 month

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 7, 2026