Diabetes Risk Reduction Through Eat, Walk, Sleep and Medication Therapy Management for Depressed Cambodians

Conditions

Depression, Diabetes

Keywords

Diabetes, Depression, Medication therapy management, Community health workers, Cambodian, Refugee, Prevention

Brief summary

The primary aim of the study is to compare the effect of three different interventions on lifestyle risk factors and biological risk factors for type 2 diabetes in depressed Cambodians. The three different interventions are lifestyle, lifestyle plus medication therapy management, and social services.

Detailed description

Cambodian Americans have high risk for major depressive disorder and for type 2 diabetes. Depression is a known risk factor for diabetes. Some antidepressants can also increase risk of diabetes by causing weight gain. DREAM will test the effect of lifestyle and medication therapy management (MTM) compared to social services (control) on diabetes risk among depressed Cambodian Americans. Community health workers (CHWs) will deliver the lifestyle intervention and assist pharmacists with MTM. Lifestyle and biological risk factors for diabetes, such as depressive symptoms, HbA1c and insulin sensitivity, will be measured before and after the interventions.

Wagner JA, Bermúdez-Millán A, Buckley TE, Buxton OM, Feinn RS, Kong S, Kuoch T, Master L, Scully MF.

2023-09-126 citations

10.1186/s12966-023-01509-y

0239 A Latent Profile Analysis of actigraphic sleep and physical activity measures among Cambodian-Americans: Relationship with specific trauma symptoms

Lindsay Master, Julie Wagner, Richard Feinn, Mary Scully, Theanvy Kuoch et al. (9 authors)

SLEEP2022-05-25

10.1093/sleep/zsac079.237

Risk factors for drug therapy problems among Cambodian Americans with complex needs: a cross-sectional, observational study

Julie Wagner, Angela Bermúdez‐Millán, S. Megan Berthold, Thomas Buckley, Orfeu M. Buxton et al. (11 authors)

Health Psychology and Behavioral Medicine2022-01-243 citations

10.1080/21642850.2021.2021917

A randomized trial to decrease risk for diabetes among Cambodian Americans with depression: Intervention development, baseline characteristics and process outcomes

Julie Wagner, Angela Bermúdez‐Millán, Thomas Buckley, Orfeu M. Buxton, Richard Feinn et al. (9 authors)

Contemporary Clinical Trials2021-05-0315 citations

10.1016/j.cct.2021.106427

Interventions

BEHAVIORALSocial Services

BEHAVIORALLifestyle

BEHAVIORALLifestyle Plus Medication Therapy Management

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

35 Years to 75 Years

Healthy volunteers

No

Inclusion criteria

* Self-identified as Cambodian or Cambodian-American * Khmer speaking * Likely major depressive disorder * Elevated diabetes risk score per ADA guidelines * Ambulatory * Competent to give consent.

Exclusion criteria

* Pregnancy or plans to become pregnant in the next 2 years * Previous diagnosis of diabetes * Seeing or hearing problems that would interfere with group sessions * Currently being followed by a physician for major medical problem * Serious thinking or memory problems (e.g., schizophrenia or dementia) * 3 or more days in a psychiatric hospital or self-harm in the past 2 years.

Design outcomes

Primary

Measure	Time frame	Description
Lifestyle risk for type 2 diabetes	12 months and 15 months	Change from baseline in depressive symptoms according to the Hopkins Symptom Checklist
Biological risk for type 2 diabetes	12 months and 15 months	Change from baseline in HbA1c and insulin resistance according to logHOMA-IR

Countries

United States

Outcome results

None listed