Colorectal Cancer
Conditions
Brief summary
(MWA) is the most recent development in the field of local ablative therapies. The aim of this study was to evaluate CT-guided percutaneous microwave (MW) ablation safety and efficacy in pulmonary metastases from colorectal cancer.
Detailed description
From June 2010 to June 2015, 48 unresectable lesions in 32 patients with pulmonary metastases from colorectal cancer were selected for CT-guided microwave ablation. Patients were scheduled for a 1 and 3 month CT follow-up to evaluate lesion diameter.We retrospectively evaluated CT-guided percutaneous microwave (MW) ablation safety and efficacy in pulmonary metastases from colorectal cancer.
Interventions
DEVICEmicrowave ablation
pulmonary metastases from colorectal cancer are destructed/ablated using microwave ablation
Sponsors
The First People's Hospital of Changzhou
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Unresectable pulmonary metastases from colorectal cancer. * diagnosis by CT, and confirmed by percutaneous puncture biopsy. * Age range 18-70 years old. * Eastern Cooperative Oncology Group performance status 0-1. * Life expectancy of more than 3 months. * Adequate organ function.
Exclusion criteria
* Resectable lung metastases. * Life expectancy less than 3 months * Patients with cardiac pacemaker, cerebral aneurysm clips, implanted electronic instruments or other metal materials. * Coagulopathy with platelet count less than 50000. * Active infectious disease. * Age below 18 years. * Pregnancy of breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Survival (OS) | one year |
Secondary
| Measure | Time frame |
|---|---|
| Treatment related adverse events | Eight weeks |
Outcome results
None listed