Nasopharyngeal Carcinoma
Conditions
Brief summary
The primary objective is to determine the early diagnosis rate and mortality rate of the Nasopharyngeal Carcinoma (NPC) in the study population. The secondary objective is to determine the incidence of NPC in the study population.
Detailed description
The research is to evaluate the effect of NPC screening, also as an extended study of Screening for Nasopharyngeal Carcinoma in High Risk Populations (NCT00941538). The program was conducted in Xiaolan and Minzhong towns of Zhongshan city in 2012. All participants will be tested for anti-EBV antibody by using serum samples. Participants are stratified into those having high, moderate and low antibody levels, those having moderate antibody levels are invited to retest annually in the following 3 years and those found to have high antibody levels on these occasions are referred to centers for diagnostic workup for NPC.
Interventions
None listed
Sponsors
Zhongshan People's Hospital, Guangdong, China
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
30 Years to 59 Years
Healthy volunteers
Yes
Inclusion criteria
* Subject residents in Zhongshan city * Subject is 30 to 59 years of age inclusive * Subject has no medical record of nasopharyngeal carcinoma * ECOG 0-2 * Subject has psychical condition and well consciousness * Subject is able to comprehend, sign, and date the written informed consent document to participate in the study.
Exclusion criteria
* Subject has heavy cardiovascular, liver or kidney disease * Subject has medical record of nasopharyngeal carcinoma * Subject who is not residing in Zhongshan City
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The early detection rate (stage I and II) of Nasopharyngeal Carcinoma | 10 years |
| The mortality rate of Nasopharyngeal Carcinoma | 10 years |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of Nasopharyngeal Carcinoma | 10 years |
Countries
China
Outcome results
None listed