Diabetic Nephropathy
Conditions
Brief summary
For diabetic patient with persisted albuminuria under the intensive control on blood pressure and blood glucose, the non-invasive method of acupressure at Sanyinjiao (SP6) is easy to use and significantly effect on albuminuria reduction in patients of diabetic nephropathy.
Interventions
DEVICEacupressure by ankle band
Sponsors
Mackay Memorial Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
1. age between 20 and 80 years old; 2. HbA1c was lower than 9% according to the NGSP(National Glycohaemoglobin Standardisation Programme); 3. estimated glomerular filtration rate (eGFR) was more than 60 mL/min/1.73 m2.
Exclusion criteria
1. Hyperglycemic crisis, including HHS(hyperglycemic hyperosmolar syndrome) and DKA(diabetic ketoacidosis ); 2. Persist diabetes poorly control, Hemoglobin A1c \[HbA1c\] \>9%; 3. Endocrine disorders: such as abnormal function of thyroid, pituitary, and sex glands; 4. heart diseases:such as arrhythmia, myocardial infarction, heart failure, or installed pacemaker; 5. immune and allergic diseases: such as systemic lupus erythematosus and asthma; 6. liver or kidney dysfunction: GOT or GPT(glutamate-pyruvate transaminase ) \> 80 IU/L, eGFR\<60 (mL/min); 7. pregnant or lactating women; 8. less than 6months postpartum; 9. acute illness, fever, Lower urinary tract infection, NSAID(nonsteroidal antiinflammatory drug) administration; 10. physical dysfunction because of stroke.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| urinary spot albumin creatine excretion ratio (UACR) change | 8 week duratoin |
Countries
Taiwan
Contacts
Primary ContactShih-Ming Chuang
Outcome results
None listed