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Relationship Between Atelectasis on Ultrasound and PaO2/FiO2

Relationship Between Intraoperative Atelectasis Findings on Transthoracic Lung Ultrasound and PaO2/FiO2

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02499536
Enrollment
26
Registered
2015-07-16
Start date
2015-07-31
Completion date
2016-04-30
Last updated
2016-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atelectasis, Postoperative

Keywords

Atelectasis, Postoperative, Lung ultrasound

Brief summary

The aim of this study is to find out relationship between PaO2/FiO2 and atelectasis finding on intraoperative lung ultrasound.

Detailed description

Patients aged 20\ 65 with ASA class (American Society of Anesthesiologists physical status classification) 1 or 2 who are scheduled to undergo general anesthesia by using endotracheal intubation and arterial line cannulation will participate in this study. The patients with abnormal chest x-ray finding, pregnancy, arrhythmia, ischemic heart disease will be excluded from this study as well as the patients who are scheduled to undergo lung or heart surgery. After 5 minutes preoxygenation, patients will be monitored with pulse oxymetry, noninvasive blood pressure. General anesthesia will be proceeded with typical method and endotracheal intubation and arterial cannulation will be proceeded. After ventilator adjustment (tidal volume as 8 times of the patient's ideal body weight), airway pressures(peak and plateau) will be recorded. Subsequently, arterial blood sampling will be proceeded while examination of the atelectasis findings on lung ultrasound before surgery. Lung ultrasound examination will be proceeded on 6 sections of patient's basal segments of the lung, including anterior, lateral, posterior segment. Juxtapleural consolidation, loss of A lines, presence of B lines, air bronchogram, loss of sliding sign and presence of pulse sign on lung ultrasound finding will be investigated and recorded. Same ultrasound examination and arterial blood sampling will be followed after surgery ends. The results of PaO2/FiO2 on arterial blood samplings will be compared with findings on lung ultrasound before and after surgery.

Interventions

DEVICEultrasound

Juxtapleural consolidation, loss of A lines, presence of B lines, air bronchogram, loss of sliding sign and presence of pulse sign on lung ultrasound finding will be investigated and recorded.

Sponsors

Severance Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Patients aged 20\ 65 * with ASA class 1 or 2 * who are scheduled to undergo general anesthesia by using endotracheal intubation and arterial line cannulation

Exclusion criteria

* The patients with abnormal chest x-ray finding, * pregnancy, * arrhythmia, * ischemic heart disease

Design outcomes

Primary

MeasureTime frameDescription
Intraoperative lung ultrasound for atelectasisBaseline (Before surgery begins) and Postoperative (Just after the surgery ends)Lung ultrasound examination for atelectasis findings (eg. whether there is a loss of A line or presence of B lines before and after surgery)
Change in PaO2/FiO2Baseline (Before surgery begins) and Postoperative (Just after the surgery ends)Arterial blood sampling to find out whether their is a change in PaO2/FiO2 before and after surgery.

Secondary

MeasureTime frameDescription
Airway pressure changeBaseline (Before surgery begins) and Postoperative (Just after the surgery ends)To find out if there is any difference between preoperative and postoperative airway pressures(peak and plateau pressure), monitored by ventilator used during general anesthesia in mmHg

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026