Interstitial Lung Disease
Conditions
Keywords
interstitial lung disease, neuromuscular electrical stimulation, exercise capacity, quality of life
Brief summary
Decreased exercise capacity and quality of life, increased dyspnea and fatigue perception and hypoxemia during exercise is seen in patients with interstitial lung disease. Impaired ventilatory response, increased lung compliance, ventilation-perfusion mismatching and inadequate peripheral circulation causes decreased exercise capacity. Another important factor that induce decreased exercise capacity is peripheral muscle weakness. In literature, there is no study investigated effects of neuromuscular electrical stimulation on functional exercise capacity, respiratory and peripheral muscle strength, pulmonary functions, physical activity level, dyspnea and fatigue perception in patients with interstitial lung disease.
Detailed description
In literature, there was increased quantity of study investigated effects of neuromuscular electrical stimulation in chronic lung disease patients. It was used as a pulmonary rehabilitation component especially in patients with decreased exercise capacity and peripheral muscle strength, intensely increased dyspnea inhibits exercise. It was demonstrated that neuromuscular electrical stimulation improved functional exercise capacity, peripheral muscle strength and quality of life.
Interventions
OTHERNMES Group
Neuromuscular electrical stimulation
OTHERControl Group
Breathing exercises
Sponsors
Gazi University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosed with interstitial lung disease * Clinically stable * Under standard medication * Having no exacerbation or infection
Exclusion criteria
* Cognitive disorders * Orthopedic and neurological problems * Contraindications to apply the neuromuscular electrical stimulation (pace maker, sensory defects, etc...)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Functional exercise capacity | 6 weeks | Six minute walk test |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Inspiratory and expiratory muscle strength (MIP,MEP) | 6 weeks | Mouth pressure device |
| Dyspnea | 6 weeks | Modified Borg and Modified Medical Research Council (MMRC) Dyspnea scales |
| Peripheral muscle strength | 6 weeks | Hand held dynamometer |
| Maximal exercise capacity | 6 weeks | Incremental shuttle walk test |
| Fatigue | 6 weeks | Fatigue Severity Scale |
| Pulmonary functions | 6 weeks | Spirometry |
| Cough related quality of life | 6 weeks | Leicester Cough Questionnaire |
| Depression | 6 weeks | Montgomery Asberg Depression Rating Scale (MADRS) (Turkish versions of all scales) |
| Generic quality of life | 6 weeks | Short Form (SF-36) Health Survey |
| Disease specific quality of life | 6 weeks | Saint George Quality of Life Questionnaire |
| Physical activity | 6 weeks | Metabolic holter |
Countries
Turkey (Türkiye)
Outcome results
None listed