Children
Conditions
Keywords
C-reactive Protein, Primary Health Care, Child Welfare, After-Hours Care, Anti-Bacterial Agents, Drug Prescriptions
Brief summary
Viral self-limiting infections in respiratory organs among children are common in primary care. Serious infections have low prevalence and are challenging to distinguish from self-limiting infections. Prescription of antibiotics in primary care is still high but stable since 2009 in Norway, and 90% of all antibiotics are prescribed in primary care. C-reactive protein (CRP) has been especially popular in Norway for point-of-care testing in primary care, but its role in ruling-out serious infections and the cut-off value for prescribing antibiotics has been discussed a lot. The aim of this study is to identify if pretesting with CRP of all children 0-6 year with fever or respiratory symptoms at Out-of-Hours Services will affect the prescription of antibiotics and the referral to hospital for children.
Detailed description
Design: A randomized controlled observational study including children 0-6 year with fever and/or respiratory symptoms at 4 different Out-of-hour Services and at 1 Emergency Children Department Clinic at a hospital (open clinic). The data consist of clinical data and anamnestic information from a nurse at OOH-service collected before the consultation, the doctor's journal and a questionnaire to parents before the consultation and 1 week after the consultation.
Interventions
Use of CRP test on all children with fever before the consultation (intervention) compared to where the doctor requests a CRP test (no intervention)
Sponsors
Study design
Eligibility
Inclusion criteria
* Children 0-6 years with fever and/or respiratory symptoms
Exclusion criteria
* Children older than 6 years with other conditions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Antibiotic prescription rate | 24 hours | Number of participants prescribed antibiotics |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Duration of illness | 7 days | Number of days with fever and respiratory symptoms after the consultation at the Out-of-hours Service. |
| Hospitalization rate | 24 hours | Number of participants referred to hospital |
| Rate of side-effects of antibiotics | 7 days | Number of participants with side-effects of antibiotics prescribed at Out-of-hours Service |