Apathy, Behavior, Frontotemporal Dementia
Conditions
Keywords
Apathy, Goal-directed behavior, Quantitative evaluation, Sensor, Ethogram
Brief summary
The purpose of this study is to provide relevant quantitative evaluation of apathy close to real life situation by means of a multimodal sensor system integrated.
Detailed description
The investigators try to measure the amount of goal-directed behaviour and to detect the pattern of apathy. The main objective of this pilot phase is to select the variables of goal-directed behaviour from the list of metrics providing by the multimodal acquisition system in healthy subjects and patients with frontotemporal dementia.
Interventions
BEHAVIORALEvaluation of Apathy Close to Real Life Situation
Quantitative Evaluation of Apathy Close to Real Life Situation by Means of a Multimodal Sensor System Integrated.
Sponsors
Institut National de la Santé Et de la Recherche Médicale, France
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 85 Years
Healthy volunteers
Yes
Inclusion criteria
* Diagnosis of Frontotemporal Dementia (FTD) according to diagnostic criteria reported by Rascovsky et al. (2011). * Understanding of the instructions and capacity to realize the cognitive tasks. * Capacity to read, to understand and to sign legal document of information * Capacity for informed consent for research, capacity to sign consent * MMSE score \> 20 * Absence of other cerebral pathology. * Absence of psychiatric disease interfering with the assessment of the tests * Absence of excessive psychotropic use * Access to National Healthcare Insurance * Accompanied with a caregiver
Exclusion criteria
* Excessive psychotropic use * Incapacity or refusal to realize the experimental tasks * Subject deprived of freedom by an administrative or court order * Subject under legal protective measure. * Incapacity for informed consent for research * Participation in another biomedical research * Airway obstruction risk * Reduction of activity not attributable to another chronic pathological condition
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Occurrence of each behavior from the ethogram | 45 min | \[Provided by the video recording and The Observer NOLDUS software\] |
| Frequency of each behavior from the ethogram | 45 min | \[Provided by the video recording and The Observer NOLDUS software\] |
| Duration of each behavior from the ethogram | 45 mn | \[Provided by the video recording and The Observer NOLDUS software\] |
| Number of different behaviors | 45 mn | \[Provided by the video recording and The Observer NOLDUS software\] |
| Activity classes | 45 mn | \[Provided by the MOVE MOVISENS sensor\] lying, sitting, ... |
| Body positions | 45 mn | \[Provided by the MOVE MOVISENS sensor\] lying left, ... |
| Energy expenditure | 45 mn | \[Provided by the MOVE MOVISENS sensor\] kcal. |
| MET | 45 mn | \[Provided by the MOVE MOVISENS sensor\] The Metabolic Equivalent of Task. MET level. |
| Steps | 45 mn | \[Provided by the MOVE MOVISENS sensor\] Counting steps. |
| Activity intensity | 45 mn | \[Provided by the MOVE MOVISENS sensor\] g. |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORRichard LEVY, PhD, MD
INSERM UMR_S 1127, ICM
Outcome results
None listed