Adenomyosis, Uterine Leiomyoma
Conditions
Keywords
adenomyosis, uterine myoma, lower urinary tract symptoms, sexual dysfunction, gastrointestinal symptom
Brief summary
The aim of this study is to assess the relationship between adenomyosis/myoma and lower urinary tract symptoms, sexual function and gastrointestinal symptoms.
Detailed description
All outpatient patients were found to have \>3 cm uterine myoma or adenomyosis were invited to participate in this study. The size and location of uterine myoma or adenomyosis and the uterus should be assessed by ultrasonography. Besides, all enrolled female patients will be asked to complete overactive bladder symptom score, female bladder function (UDI-6 & IIQ-7), female sexual function index, and bowel incontinence assessment questionnaires. In addition, patients who underwent surgeries for myoma or adenomyosis will be requested to complete the above questionnaires at 3 months after surgery. Women with intact uterus should be assessed again by ultrasonography. At least 30 women with age and body mass index matched and without uterine myoma or adenomyosis will be invited to participate in this study as the control group.
Interventions
PROCEDUREmyomectomy or adenomyomectomy
Sponsors
Far Eastern Memorial Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
\<Women with myoma or adenomyosis\> Inclusion Criteria: 1. \>20 years old. 2. Myoma: women with \>3 cm uterine myoma 3. Adenomyosis: women with uterus having several dark area (lacunar areas) in one uterine wall or thickening uterine wall \<The control group\> Inclusion criteria: 1. \>20 years old. 2. Women without myoma or adenomyosis \<Both groups\>
Exclusion criteria
1. The patient has a lower urinary tract infection or acute intestinal inflammation. 2. Previous surgery for the bladder or urethra. 3. History of urinary tract stones or tumors.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The corrleation coefficient between the size of myoma and Overactive Bladder Symptoms Scores | 12 weeks | The Spearman's correlation between the size of uterine myoma and the score of Overactive Bladder Symptoms Scores |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The corrleation coefficient between the size of myoma and the presence of constipation/diarrhea | 12 weeks | The Spearman's correlation between the size of uterine myoma and the presence of constipation/diarrhea |
| Comparison of Overactive Bladder Symptoms Scores between the adenomyosis group and the control group | 12 weeks | Comparison of Overactive Bladder Symptoms Scores between the adenomyosis group and the control group by Wilcoxon rank-sum test |
| Comparisons of the constipation/diarrhea rates between the adenomyosis group and the control group | 12 weeks | Comparisons of the constipation/diarrhea rates between the adenomyosis group and the control group by Chi-square test or Fisher's exact test |
Countries
Taiwan
Contacts
Primary ContactSheng-Mou Hsiao, MD
Outcome results
None listed