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Effect of Low-level Laser Therapy on Exercise-induced Muscle Damage

Effect of Low-level Laser Therapy on Exercise-induced Muscle Damage: a Randomized Clinical Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02493556
Enrollment
12
Registered
2015-07-09
Start date
2015-06-30
Completion date
2015-09-30
Last updated
2015-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle Damage

Keywords

Phototherapy, Plyometric exercise, Muscle recovery

Brief summary

Introduction: The effects of Low Level Laser Therapy (LLLT) on exercise-induced muscular damage have been studied over the last years. Studies have been conducted on animals and humans in order to try to show the benefits of the intervention, but there is still conflicting evidence about its protective and therapeutic effects. Objectives: To describe the effects of LLLT on pain, strength and muscular inflammation after plyometric exercise. Methods: A randomized, double-blinded, placebo-controlled trial with participation of 20 male healthy volunteers will be performed. Healthy and physically active individuals, aged between 18 and 35 years, with no history of injury on the lower limbs or contra-indications to maximal exercise performance will be included. A protocol of 10 series with 10 repetitions of the countermovement jump will be used to induce muscle damage at the lower limbs. Immediately before or after the exercise protocol, LLLT will be applied on one lower limb, while the other will receive placebo treatment. Phototherapy will be applied with an equipment of 810nm and a cluster with 5 diodes on 8 different points of the knee extensor muscle, totalizing a dosage of 240J. The placebo treatment will be held on the same way, but the equipment will be turned off. The volunteers will be evaluated at baseline (before the exercise protocol) and at follow-up of 24, 48 and 72 hours. The following outcomes will be evaluated: knee extensors isometric peak torque by Isokinetic Dynamometer, pain by Visual Analogue Scale and muscular tissue echo intensity by Ultrasonography.

Interventions

DEVICELLLT before muscle damage
DEVICEPlacebo LLLT before muscle damage
DEVICELLLT after muscle damage
DEVICEPlacebo LLLT after muscle damage

Sponsors

Federal University of Health Science of Porto Alegre
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
MALE
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy males aged between 18 and 35 years; * Sedentary or physically active individuals who exercise up to 3 times per week.

Exclusion criteria

* Individuals who participate in systematic exercise training; * Individuals who participate in strength training for the lower limbs; * Individuals with lower or upper limb injuries; * Individuals with contra-indications to maximal exercise performance (due to neurological, cardiovascular or respiratory conditions); * Individuals who show difficulties to understand the study protocol.

Design outcomes

Primary

MeasureTime frameDescription
Knee extensors isometric peak torque (Nm)Baseline and 24, 48 and 72 hours follow-upIsokinetic Dynamometer

Secondary

MeasureTime frame
Knee extensors soreness (Visual Analogue scale)Baseline and 24, 48 and 72 hours follow-up
Knee extensors echo intensity (number of white and black pixels)Baseline and 24, 48 and 72 hours follow-up

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026