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Effect of Smoking Cessation on Non-surgical Periodontal Therapy

Effect of Smoking Cessation on Non-surgical Periodontal Therapy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02493270
Acronym
EsCAPE
Enrollment
177
Registered
2015-07-09
Start date
2007-05-31
Completion date
2014-06-30
Last updated
2016-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Keywords

smoking cessation, tobacco, dental, periodontal

Brief summary

The aim of this prospective study is to verify the efficacy of smoking cessation on non-surgical periodontal therapy in adult subjects with chronic periodontitis. Smokers that were willing to quit received periodontal treatment and concurrent smoking cessation therapy. Periodontal maintenance was performed every 3 months. A calibrated examiner, blinded to smoking status, assessed periodontal status, gathered demographic and behavioural information with a structured questionnaire and measured air carbon monoxide concentration measurements.

Interventions

Multidisciplinary smoking cessation therapy, performed by a team comprising physicians, nurses, a psychologist and dentists. It consisted of four 1-h counselling lectures, psychologist-assisted cognitive behavioural therapy, nicotine replacement therapy and medication (bupropion or varenicline). Smoking cessation motivation was reinforced by dentists at the maintenance sessions, by means of motivational interviewing techniques

PROCEDURENon-surgical periodontal therapy

full-mouth supra and subgingival scaling and root planing (with curettes and ultrasonic scaler); oral hygiene instruction and motivation and removal of intra-oral plaque retentive factors

Sponsors

University of Sao Paulo
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* subjects were willing to stop smoking * \>10 teeth * periodontitis (30% or more of their teeth with proximal CAL ≥ 5 mm

Exclusion criteria

* systemic conditions considered as risk factors for periodontal disease, * periodontal therapy in the last 6 months * continuous systemic use of anti-inflammatory or steroidal drugs

Design outcomes

Primary

MeasureTime frame
Change in Clinical Attachment Level (millimeters) after 24 monthsbaseline and 24 months

Secondary

MeasureTime frame
Change in Gingival recession (millimeters) after 24 monthsbaseline and 24 months
Change in Pocket depth (millimeters) after 24 monthsbaseline and 24 months
Change in bleeding on probing (percentage of sites with bleeding) after 24 monthsbaseline and 24 months
Change in visible plaque (percentage of sites with visible plaque) after 24 monthsbaseline and 24 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026