Ketoprofen Gel vs Placebo in Low Back Pain

Ketoprofen Gel vs Placebo in Patients Presented With Low-back Pain to Emergency Department: A Ranodmized Controlled Trial

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02491879

Enrollment

100

Registered

2015-07-08

Start date

2015-06-30

Completion date

2016-01-31

Last updated

2015-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanical Low Back Pain

Keywords

mechanical low back pain, emergency department, ketoprofen, gel

Brief summary

This study aimed to analyse the analgesic effect of ketoprofen gel in patients presented with mechanical low-back pain to the emergency department.

Detailed description

Mechanical low-back pain which warrants immediate pain relief is not an infrequent symptom for emergency department physicians to deal with. Parenteral analgesic is the most common drugs for the these patients in emergency department. However, pain killers in gel forms have not been studied sufficiently for ceasing the pain of these patients. This study aimed to analyse the analgesic effect of ketoprofen gel in patients presented with mechanical low-back pain to the emergency department.

Interventions

DRUGKetoprofen

2.5% Ketoprofen gel with a 2 g local use

OTHERPlacebo

Placebo gel with a 2 g local use

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Patients over 18 and lower 65 years old * Patients presented with mechanical low-back pain

Exclusion criteria

* Pain more than 24 hours * Pain lower than with a pain score of 40 mm * Allergy to ketoprofen * Drug or alcohol addiction * pregnancy and breast feeding

Design outcomes

Primary

Measure	Time frame	Description
Visual Analogue Scale	30 minutes	Pain reduce will be measured by visual analogue scale score at 30 minutes

Secondary

Measure	Time frame
Adverse outcome	30 minutes

Countries

Turkey (Türkiye)

Contacts

Primary ContactMustafa Serinken, MD

aserinken@hotmail.com00905052991497

Backup ContactCenker Eken, MD

cenkereken@akdeniz.edu.tr00905321593948

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026