Colorectal Neoplasms
Conditions
Keywords
fecal occult blood
Brief summary
The aim of this study is to compare the outcome of three (3) quantitative immunochemical faecal occult blood test in symptomatic patients.
Detailed description
Consecutive patients referred from primary care for colonoscopy due to symptoms are eligible. Patients will receive written information of the study together with the time for colonoscopy. A specific research nurse will call them and for those accepting participation, history and current medication will be collected. Kits will be sent to patients and they will provide three faecal samples before examination. These will be analysed at one certified laboratory. Hemoglobin concentration will be notified in the range of 50 - \< 1000 ng/mL, or as a negative outcome. Macroscopic findings at the colonoscopy will be collected, as well as the outcome of the pathological report.
Interventions
DEVICEfecal occult blood test
Sponsors
Uppsala University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Symptoms associated with colorectal cancer (anemia, change of bowel habits, diarrhoea, constipation, haematochezia, weight loss, anorexia)
Exclusion criteria
* Screening investigations * High-risk patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of patients with high fecal blood output in relation to colorectal cancer | Up to 36 months | Accuracy of diagnosis in colorectal cancer |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of patients with low fecal blood output in relation to colorectal polyps | Up to 36 months | Accuracy of diagnosis of colorectal polyps |
Countries
Sweden
Outcome results
None listed