Healthy
Conditions
Brief summary
The purpose of this study is to compare the effects of different dose of whey protein intervention(in a daily dose of 0g, 10g, 20g) on lean body mass,body fat composition and muscular function state in the elderly with sacropenia.
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
* People aged over 65 years. * Usual gait speed less than 0.8m/s. * Willing to participate in the study, consume the test product and perform all measurements.
Exclusion criteria
* nervous system disease. * Other diseases with movement disorder such as stroke,fracture,arthritis. * people who unconsciousness and can not complete questionnaire * long-term regular use of protein and antioxidant.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| lean body mass | up to 6 months | At baseline, 3 and 6 months, investigators will use DXA to examine lean body mass and body fat composition |
| muscular function state | up to 6 months | At baseline, 3 and 6 months, investigators will use the Short Physical Performance Battery (SPPB) to test muscular function state |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| plasma amino acid spectrum, especially branched chain amino acid spectrum | up to 6 months | At baseline and 6 months, blood samples will be drawn and plasma amino acid spectrum, especially branched chain amino acid spectrum will be tested |