Epidemiology of Acute Respiratory Distress Syndrome in Chinese ICUs

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02490215

Enrollment

2530

Registered

2015-07-03

Start date

2015-01-31

Completion date

2015-12-31

Last updated

2020-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome

Brief summary

The acute respiratory distress syndrome(ARDS)has a high morbidity and mortality in patients admitted to intensive care units(ICUs). It represents a significant public health issue. No large nationwide, multicenters study of ARDS has been conducted in China. The purposes of this study are to analyse: 1)the incidence and outcomes of ARDS in ICU; 2) factors associated the mortality ; and 3) risk factors for development of ARDS .

Detailed description

All patients admitted to the participating ICUs during a 6-month period(from January 1, 2015 to July 1,2015 ) will be screened at ICU admission and daily for the occurrence of ARDS ( AECC criteria) for a maximum of 28 days after ICU admission. Data collection: 1. For all patients, Demographic characteristics, admission category, the patient source intervention during ICU , APACHEII , SOFA score and discharge information will be collected 2. For patients with ARDS, data about ABG , parameters of MV, hemodynamic on day0 to day7 and last day of MV will be collected. 3. For patients without ARDS at ICU admission, data about risk factor for ARDS ,such as LIPS score, parameters of MV , and fluid balance on ICU day0 to day7 will be collected.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

all patients age \>18 yrs admitted to 24 participating ICUs

Exclusion criteria

No patients should be excluded (regardless of age, underlying disease, life expectancy, etc).

Design outcomes

Primary

Measure	Time frame	Description
incidence of acute respiratory distress syndrome (ARDS)	from ICU admission to 28-day of ICU stay	incidence of ARDS = the number of patients developing ARDS during ICU / the total number of patients admitted to ICU

Secondary

Measure	Time frame
ICU mortality of patients with ARDS	followed up to 3 months after inclusion or to ICU discharge, whichever occurred first
hospital mortality of patients with ARDS	followed up to 3 months after inclusion or to hospital discharge, whichever occurred first

Countries

China

Outcome results