The Effects of Using Fertile Chip in Sperm Selection for Intracytoplasmic Sperm Injection in Unexplained Infertility

The Effectiveness of Using Fertile Chip on Intracytoplasmic Sperm Injection Undergoing Ivf Programme in Unexplained Infertile Couples

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02488434

Enrollment

122

Registered

2015-07-02

Start date

2015-06-30

Completion date

2016-08-31

Last updated

2016-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unexplained Infertility

Keywords

ICSI, sperm selection, fertile chip, ıcsı outcomes

Brief summary

The aim of the current study is to evaluate to effectiveness of sperm selection by using fertile chip in unexplained infertile couples on intracytoplasmic sperm injection (ICSI) cycles.

Detailed description

The aim of the current study is to evaluate to effectiveness of sperm selection by using fertile chip in unexplained infertile couples on intracytoplasmic sperm injection (ICSI) cycles. On study arm sperm selection will be performed by using special microchannel system which is called fertile chip (FC) without using sperm wash procedure. This FC system leads to select lineer motile progressive sperm selection. In control group, sperm selection will be performed by classical way which sperm will be undertaken to sperm wash by gradient method. After selection of sperm in both arms, ICSI will be performed. The outcomes of ICSI schedule will be assesed by fertilization and clinical pregnancy rates.

Interventions

DEVICEfertile chip

a new method for sperm selection on ivf cycles by using microchannel system.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

20 Years to 40 Years

Healthy volunteers

Inclusion criteria

* between 20-37 year-old women * normal tubal patency, normal uterine cavity, normal ovulation, * between 20-40 year-old men * normal semen analyse by WHO criterias * unexplained infertile couples

Exclusion criteria

* poor ovarian reserve which is diagnosed by Bologna criterias * abnormal semen analyse by WHO sperm criterias * abnormal ovulation problems,tubal patency or uterine cavity

Design outcomes

Primary

Measure	Time frame
increase fertilisation rate	2 days

Secondary

Measure	Time frame
Clinical pregnancy rates	10 months

Other

Measure	Time frame
The number of freezing embryos	6 months

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 4, 2026