Anesthesia Complications
Conditions
Keywords
Epidural, Analgesia labor, Perinatal, anesthesia
Brief summary
The investigators study the efficacy of epidural sufentanil/ropivacaine for analgesia labor in primiparas so as to decrease perinatal complications of analgesia labor.
Detailed description
A prospective study of 120 full-term parturients receiving labor analgesia were randomly assigned into 2 groups: the 0.5Sufen group (N=60), the 0.25Sufen group (N=60).
Interventions
DRUG0.25 sufentanil
with different dosage
DRUG0.5µg/ml sufentanil
0.5µg/ml sufentanil
DRUG0.1% ropivacaine
0.1% ropivacaine
Sponsors
Shanghai Jiao Tong University School of Medicine
Fudan University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
FEMALE
Age
25 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
1. Patients had regular prenatal examinations at the outpatient clinic; 2. They were between 25 to 35 years of age) 3. They had a gestational age ≥37 weeks and \< 42 weeks; 4. They had an estimated fetal weight ≥ 2,500 g and \< 4,200 g.
Exclusion criteria
* a history of spinal surgery, * platelet count \<100×109 /L , * coagulation disorder, * sensorimotor disorder of lower extremity, * leg pain, * puncture point infection, * heart disease history, * pulmonary disease, * liver and renal function disorder and * a history of neuropsychiatry drugs.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| VAS(visual analog pain score) | 1 year | comparison with two groups |
Outcome results
None listed