Effects of an Amino Acid and Chromium-picolinate Containing Drink on Glucose Metabolism on Healthy Subjects

Effect of a Table Water Enriched With Amino Acids and Chromium on Blood Glucose and Insulin Levels After a Meal

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02487680

Enrollment

Registered

2015-07-01

Start date

2015-06-30

Completion date

2015-11-30

Last updated

2017-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes

Brief summary

It has previously been shown in healthy overweight subjects, that table water including a defined amount of amino acids and chromium can decrease the postprandial glucose. In this study, the effect of this table water on glucose excursions after a test meal containing a defined amount of available carbohydrates, protein and fat will be studied in healthy subjects. The study will be conducted in a cross -over design, double blinded and placebo controlled including 20 participants. The primary endpoint of the study is the incremental area under the curve for plasma glucose (iAUCgluc) within 180 minutes after ingestion of the meal.

Interventions

DIETARY_SUPPLEMENTAmino Acids and chromium-picolinate containing drink

Evaluation of the dietary supplement drink containing amino acids and chromium picolinate and aroma

DIETARY_SUPPLEMENTPlacebo drink

Evaluation of the placebo supplement drink containing only aroma

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Stable body weight (no changes above 3 kg during the last 2 months) * Good general health * Body mass index 19 - 30 kg/m2 (normal to overweight) * Fasting blood glucose below 6.1 mmol/L

Exclusion criteria

* Any medication that could influence the study. Such as medication against diabetes, hypoglycemia, hypertension or hypercholesterolemia * Psychiatric Disease * Alcohol or drug abuse * Smokers or people consuming snus * Acute infections * Vegetarians/vegans * Suffering from Lactose or Gluten intolerance * Pregnancy or Lactation * Participation in another study at the same time * Any other parameter that the PI will judge as inadequate

Design outcomes

Primary

Measure	Time frame
Area under the curve for Glucose after ingestion of a test meal	180 min

Secondary

Measure	Time frame
Area under the curve for insulin after ingestion of a test meal	180 min

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026