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Has Inflammation a Significant Implication in Lung Cancer Evolution?

L'Inflammation A-t-elle Une Implication Significative Dans l'évolution du Cancer Bronchique?

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02484872
Enrollment
400
Registered
2015-06-30
Start date
2015-05-31
Completion date
2023-12-31
Last updated
2021-08-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Neoplasms

Keywords

Inflammation, Glasgow score, Intensive Care Unit, Emergency

Brief summary

Systemic inflammation is a potential prognostic factor in cancer. Inflammation scores as the Glasgow score have been tested in cancer and specifically in lung cancer patients. The aim of the study is to look at the prognostic and predictive value of inflammation during cancer evolution, on the risk of complications leading to ICU admission and the risk of death.

Detailed description

Patients with newly diagnosed lung cancer will be eligible. All patients will have a blood sampling allowing testing inflammation and cytokine analyses at diagnosis, during work-up and in case of complication.

Interventions

None listed

Sponsors

Jules Bordet Institute
CollaboratorOTHER
European Lung Cancer Working Party
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Lung neoplasms irrespective of stage, histology

Exclusion criteria

* Previously treated lung neoplasms * A history of prior malignant tumour, except non-melanoma skin cancer or in situ carcinoma of the cervix or cured malignant tumour (more than 5 year disease-free interval)

Design outcomes

Primary

MeasureTime frame
SurvivalMeasured from diagnosis until death or last date known to be alive, or at least 48 months

Secondary

MeasureTime frameDescription
Complications leading to emergency/ICUFrom inclusion until death, or a least 48 monthsRecording any complication leading to consultation at the emergency department or admission into the intensive care unit

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026