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Impaired Vigilance, and Its Effects on Cognition and Behavior

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02484846
Enrollment
50
Registered
2015-06-30
Start date
2011-02-28
Completion date
2012-03-31
Last updated
2015-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Feeding Behavior, Sleep Deprivation

Brief summary

Fifty healthy, young participants (10 male, 40 female) completed two 3-hour study sessions that were at least five days apart. The first session was a baseline. The sleep intervention took place on the night prior to Session 2, where the amount of time in bed was manipulated to be 60-130% of the individual's habitual sleep time. Within both sessions, subjective (Stanford Sleepiness Scale, SSS) and objective (Psychomotor Vigilance Test, PVT) alertness were measured. During the middle of each session, a 40-minute ad libitum meal opportunity allowed participants to eat from eight different food items. Food healthfulness, caloric density, distribution and number of calories were measured and compared to alertness levels.

Interventions

BEHAVIORALTime in bed

Habitual time spent in bed for the purpose of sleep was determined at baseline. This was used to calculated the experimental time in bed the subject was to spent on the one night prior to the second lab visit.

Sponsors

Stanford University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* Age: 18-45 years * BMI: 20-29 kg/m² * Eat breakfast at least 5 days per week * Wake time occurs between 5&10AM at least 5 days per week * Time in bed for sleep between 5&10 hours at least 5 days per week

Exclusion criteria

* Dietary restrictions that prohibit them from selecting one of the food choices offered in the study (e.g., gluten allergies, diabetes, vegan diet, dairy avoidance, allergies to the respective food choices available), * are currently on a calorie-restricted diet, or * are currently at a weight that is less than 20% of their highest weight within the last three years. * Participation in shift work within 7 nights of the experiment * Diagnosed as having severe sleep apnea syndrome, narcolepsy or chronic insomnia * Diagnosed as having an eating disorder * Active serious health condition * Regularly taking vigilance-related medication (e.g., ADHD prescribed medication) * Typically consume more than 600 mg of coffee or more than 10 cigarettes per day

Design outcomes

Primary

MeasureTime frameDescription
Total calories consumed45 minutesTotal calories consumed during a 45 minute meal opportunity during the each of the two study sessions.

Secondary

MeasureTime frameDescription
Alertness15 minutesObjective alertness was determined during each of the two study sessions during a 15 minute test of sustained attention (Psychomotor Vigilance Task).

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026