Coronary Artery Disease
Conditions
Brief summary
The investigators propose a single center prospective study that will assess two different strategies for measuring Fractional Flow Reserve (FFR) in patients undergoing clinically-indicated coronary angiography in whom FFR measurement is indicated. FFR will be measured with a non-side hole guide catheter (with the guide catheter both engaged and disengaged from the coronary ostium) and with a side-hole guide catheter (with the guide catheter both engaged and disengaged from the coronary ostium) to determine, whether measurements obtained with an engaged side-hole guide catheter are more accurate as compared with those obtained with the engaged non-side hole catheter.
Interventions
OTHERFFR Measurement
Sponsors
North Texas Veterans Healthcare System
Study design
Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Undergoing a clinically indicated coronary catheterization * Need FFR of a coronary artery lesion * Agree to participate and able to provide informed consent
Exclusion criteria
* Significant difficulty advancing the pressure measuring guidewire into the coronary artery * Severe chronic obstructive pulmonary disease * Severe ostial disease (\>70% diameter stenosis within 5 mm from the coronary artery ostium)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FFR measurement using a guide catheter with and without side holes | Less than 1 hour during the coronary angiography |
Countries
United States
Outcome results
None listed