Study of Free DNA Content of Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment

Study of Cell Free DNA Content of Human Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment in ICSI Treatment Cycles

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02480491

Enrollment

100

Registered

2015-06-24

Start date

2014-01-31

Completion date

2015-05-31

Last updated

2015-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Brief summary

Study of Cell Free DNA Content of Human Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment in intra cytoplasmic sperm injection Treatment Cycles.

Detailed description

The aim of the present study is to determine whether cell free DNA content of the culture medium of the human embryo correlates with the quality and reproductive potential of embryos in ICSI cycles and, thus, to look for a new non invasive tool of assessing embryo quality beside morphological assessment. Determining a rapid, noninvasive method for the assessment of the developmental potential of embryos may be a great achievement

Interventions

OTHERmeasuring cell freeDNA

measuring cell free DNA using PCR

Study design

Observational model

COHORT

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Yes

Inclusion criteria

* third day embryos

Exclusion criteria

* less than third day embryos

Design outcomes

Primary

Measure	Time frame
correlations between levels of measured cell free DNA and embryo quality.	12 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026