3D CT Guidance for Transjugular Intrahepatic Portosystemic Shunt Creation

Guidance for TIPS Creation: CT-image Versus CO2 Portography

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02480426

Enrollment

Registered

2015-06-24

Start date

2015-06-30

Completion date

2015-12-31

Last updated

2015-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Portal Hypertension

Brief summary

To prospectively evaluate the efficacy of real-time 3D CT-image guidance and CO2 portography during transjugular intrahepatic portosystemic shunt (TIPS) creation.

Interventions

DEVICECT-image guidance

TIPS creation is performed under the guidance of 3D CT-image.

DRUGCO2 portograms guidance

TIPS creation is performed under the guidance of two-dimensional (2D) CO2 portograms.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

1. Cirrhosis 2. Scheduled for indicated TIPS procedure

Exclusion criteria

1. Presence of portal vein thrombosis 2. Presence of ascites 3. Presence of hepatic vein occlusion or stenosis 4. Proven malignancy including hepatocellular carcinoma 5. End-stage renal disease under renal replacement therapy; 6. Cardiorespiratory failure 7. Pregnancy or patients not giving informed consent for TIPS procedures

Design outcomes

Primary

Measure	Time frame
Technical success rate	procedure

Secondary

Measure	Time frame
Median needle passes for portal vein entry	procedure
Median radiographic fluoroscopy time for portal vein entry	procedure
The median radiation dose for the whole TIPS procedure	procedure
The rate of TIPS complication	6 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026