Ileus
Conditions
Keywords
Acupuncture, Gastric cancer
Brief summary
Postoperative ileus (POI) is a common problem after major abdominal surgery. Acupuncture is being accepted in the West as a treatment option for managing POI and various functional gastrointestinal disorders. Therefore, we conducted a prospective randomized pilot study to evaluate the effect of electro-acupuncture on POI and other surgical outcomes in patients who underwent gastric surgery for a later large-scale study.
Detailed description
Before surgery, patients were randomized (using simple randomization) to either acupuncture (A) group or non-acupuncture (NA) group. In both groups, sitz markers were inserted in duodenum or jejunum during surgery for detection of postoperative remnant sitz markers by Xray. In the A group, acupuncture treatment was given once daily for up to 5 consecutive days starting on postoperative day 1. The acupuncture points which were used were based on traditional Korean medicine. No acupuncture treatment was performed in the NA group.
Interventions
DEVICEacupuncture
Acupuncture treatment after gastric cancer surgery during 5 postoperative days
Sponsors
Daegu Catholic University Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients undergoing elective surgery for gastric cancers * Patients with American Society of Anesthesiologists grades I-III * Patients who provided written informed consent
Exclusion criteria
* Patients who developed intraoperative problems or complications * Patients with contraindications to had electrical stimulation devices (pacemaker or implantable defibrillator) * Patients who were allergic to acupuncture needle
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Remnant sitz markers in small intestine at postoperative day 7 | measured in postoperative day 7 | Numbers of of remnant sitz markers in the small intestine that did not pass through ileo-cecal valve, measured by X-ray on postoperative day 7. |
| Remnant sitz markers in small intestine at postoperative day 1 | measured in postoperative day 1 | Numbers of of remnant sitz markers in the small intestine that did not pass through ileo-cecal valve, measured by X-ray on postoperative day 1. |
| Remnant sitz markers in small intestine at postoperative day 3 | measured in postoperative day 3 | Numbers of of remnant sitz markers in the small intestine that did not pass through ileo-cecal valve, measured by X-ray on postoperative day 3. |
| Remnant sitz markers in small intestine at postoperative day 5 | measured in postoperative day 5 | Numbers of of remnant sitz markers in the small intestine that did not pass through ileo-cecal valve, measured by X-ray on postoperative day 5. |
Secondary
| Measure | Time frame |
|---|---|
| Time to first flatus | up to 5 dyas |
| start of water intake | up to 7days |
| start of soft diet | up to 7days |
| hospital stay | up to 2 weeks |
Other
| Measure | Time frame |
|---|---|
| white blood cell count in preoperative period | measured in day before operation |
| white blood cell count in postoperative day 1 | measured in postoperative day 1 |
| white blood cell count in postoperative day 3 | measured in postoperative day 3 |
| serum C reactive protein level in postoperative day 7 | measured in postoperative day 7 |
| white blood cell count in postoperative day 7 | measured in postoperative day 7 |
| serum C reactive protein level in preoperative period | measured in day before operation |
| serum C reactive protein level in postoperative day 1 | measured in postoperative day 1 |
| white blood cell count in postoperative day 5 | measured in postoperative day 5 |
| serum albumin level in preoperative period | measured in day before operation |
| serum albumin level in postoperative day 1 | measured in postoperative day 1 |
| serum albumin level in postoperative day 3 | measured in postoperative day 3 |
| serum albumin level in postoperative day 5 | measured in postoperative day 5 |
| serum albumin level in postoperative day 7 | measured in postoperative day 7 |
| serum C reactive protein level in postoperative day 3 | measured in postoperative day 3 |
| serum C reactive protein level in postoperative day 5 | measured in postoperative day 5 |
Outcome results
None listed