Bone Mineral Density Quantitative Trait Locus 3
Conditions
Brief summary
BMD at peripheral sites typically heel is measured by Ultrasound densitometry at Ain Shams Maternity hospital.
Detailed description
Consecutive patients with singleton pregnancies between 36 and 39 weeks booked at a general obstetric clinic in a regional hospital will be recruited for the study. The obstetric department is a tertiary referral center in the region and part of a university teaching unit which catered to an annual delivery of around 10,000 women. A group of first trimester pregnant women with nearly the same age is recruited as controls.
Interventions
RADIATIONcalcaneal quantitative ultrasound assessment
QUS for calcaneus bone of right foot will be done for this group of Pregnant women at the third trimester
Sponsors
Ain Shams University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
1\. females during 3rd trimister
Exclusion criteria
1. Secondary causes of bone loss such as hyperparathyroidism. 2. Co-morbidities that would interfere with bone metabolism as clinically significant liver or renal disease. 3. Physical or orthopedic disabilities that would place the subject at risk or limit their ability to perform US. 4. Taking medication known to affect bone including steroid hormones. Histories of smoking and use of oral contraceptives (OCs) are not
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone mineral density loss during pregnancy that is detectable by quantitative ultrasound at the os calcis. | 6 months |
Countries
Egypt
Outcome results
None listed