Effects of Mineralocorticoid Receptor Stimulation on Cognition

Effekte Von Fludrocortison Auf Soziale Kognition Und Gedächtnis Unter Berücksichtigung Von Geschlechtereffekten

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02478034

Acronym

MR-STIM

Enrollment

Registered

2015-06-23

Start date

2015-05-31

Completion date

2016-03-31

Last updated

2016-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Individuality

Brief summary

In this study the effects of mineralocorticoid stimulation on social cognition will be investigated in healthy young individuals.

Detailed description

80 healthy young individuals (40 females and 40 male) will be recruited an randomized to either placebo or 0.4 mg Fludrocortison before testing. Tasks will on emotion recognition, Task Switch, visual spacial memory and decision making will be conducted.

Interventions

OTHERFludrocortisone

effects of fludrocortisone on cognition compared to placebo

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 30 Years

Healthy volunteers

Yes

Inclusion criteria

* free of medication * age 18 - 30

Exclusion criteria

* any medication * severe illness

Design outcomes

Primary

Measure	Time frame	Description
social cognition	25 min	computer based tests: emotion recognition

Secondary

Measure	Time frame	Description
memory	20 min	computer based test on visuospacial memory
decision making	25 min	computer based tests: BART

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026