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Consistencies in Responses to Sodium Bicarbonate?

Consistencies in Responses to Sodium Bicarbonate Supplementation: a Randomised, Repeated Measures, Counterbalanced and Double-blind Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02474628
Enrollment
15
Registered
2015-06-18
Start date
2013-11-30
Completion date
2014-06-30
Last updated
2015-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sports Nutritional Physiological Phenomena

Keywords

Physiological Phenomena

Brief summary

Intervention studies do not account for high within-individual variation potentially compromising the magnitude of an effect. Repeat administration of a treatment allows quantification of individual responses and determination of the consistency of responses. The investigators aim to determine the consistency of metabolic and exercise responses following repeated administration of sodium bicarbonate (SB). Design and Methods: 15 physically active males will complete six cycling capacity tests at 110% of maximum power output (CCT110%) following ingestion of either 0.3 g∙kg-1Body Mass of SB (4 trials) or placebo (PL, 2 trials). Blood pH, bicarbonate, base excess and lactate will be determined at baseline, pre-exercise, post-exercise and 5-min post-exercise. Total work done (TWD) will be recorded as the exercise outcome.

Interventions

DIETARY_SUPPLEMENTsodium bicarbonate
DIETARY_SUPPLEMENTcalcium carbonate

Sponsors

University of Sao Paulo
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* recreationally active males

Exclusion criteria

* use of dietary supplements in the past 6 months * the presence of any musculoskeletal disorder * the use of anabolic steroids

Design outcomes

Primary

MeasureTime frame
blood pH5 min after a physical exercise test

Secondary

MeasureTime frameDescription
blood bicarbonate5 min after a physical exercise test
blood lactate5 min after a physical exercise test
anaerobic exercise capacity4 hours after supplementationas assessed by cycling capacity tests at 110% of maximum power output

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 3, 2026