Dupuytren Disease
Conditions
Brief summary
The efficiency of percutaneous aponeurotomy in the treatment of Dupuytrens disease is well known. However, the duration of the clinical improvement after aponeurotomy is not well known. This study aims primarily at measuring the incidence rate of local relapse of Dupuytrens-induced finger flessum, within two years following treatment by percutaneous aponeurotomy in Dupuytrens.
Interventions
PROCEDUREPercutaneous aponeurotomy
The finger(s) with limited extension due to Dupuytrens disease and for which the patient desires treatment, will be treated by fine-needle percutaneous aponeurotomy under local anesthesia (outpatient procedure). This procedure is already routinely used in clinical practice ; our study aims at better describing the time-sustainability of its benefits.
Sponsors
Groupe Hospitalier Diaconesses Croix Saint-Simon
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient suffers from Dupuytren disease * Patient has at least one finger with at least 20° flessum on the metacarpophalangeal joint and/or on the proximal interphalangeal joint * Patient has chosen to benefit from local treatment
Exclusion criteria
* Pregnancy * Breastfeeding * No social insurance
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Frequency of local relapse at 24 months | 24 months after treatment by aponeurotomy | the statistical unit is the finger treated by aponeurotomy (we expect an average of 2 fingers treated for one patient included). Local relapse is defined as the recurrence of a finger flessum superior by 20° to the articular range initially obtained after aponeurotomy |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Primary success rate of aponeurotomy | 3 months after treatment | the statistical unit is the finger treated by aponeurotomy (we expect an average of 2 fingers treated for one patient included). Complete success is defined as a finger flessum inferior to 5° |
| Frequency of local relapse at 12 months | 12 months after treatment by aponeurotomy | — |
| Frequency of local relapse at 36 months | 36 months after treatment by aponeurotomy | — |
| Frequency of local relapse at 48 months | 48 months after treatment by aponeurotomy | — |
| Frequency of local relapse at 60 months | 60 months after treatment by aponeurotomy | — |
Countries
France
Outcome results
None listed