Hypotension
Conditions
Brief summary
A group of engineers at Michigan State developed a novel waveform analysis technique (Long Time Interval Analysis \[LTIA\]) that attempts to estimate cardiac output non-invasively. Retrospective comparison of LTIA to invasive techniques (e.g. thermodilution) suggest acceptable agreement. Thus, a prospective trial of LTIA is warranted. This study compares LTIA to a validated measure of cardiac output - esophageal Doppler monitoring.
Interventions
DEVICERetia Medical Long Time Interval Analysis
Retia Medical Long Time Interval Analysis will be used to analyze the blood pressure tracing of patients having surgery who have an arterial catheter
Sponsors
University of Virginia
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult (18 years or older) * Undergoing hepatobiliary surgery (open or laparoscopic) requiring general anesthesia as part of the patient's clinical care * Attending anesthesiologist plans to place an intra-arterial catheter for routine care * Attending anesthesiologist believes that non-invasive cardiac output monitoring would benefit the patient
Exclusion criteria
* Minors (17 years or younger) * Parturient (pregnant women) * Cognitively impaired * Unable to sign informed consent form * Prisoner * Prior esophageal surgery * Moderate to severe aortic regurgitation * Mechanical cardiac support (e.g., intra-aortic balloon pump) * Severe, persistent arrhythmias
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pearson Correlation Coefficient | Data collected in first 20 minutes of anesthesia/surgery will be recorded; Pearson correlation coefficient will be calculated after all 60 subjects have been enrolled | Correlation between change in CO from LTIA vs. change in CO from esophageal Doppler |
Countries
United States
Contacts
Primary ContactRobert H Thiele, M.D.
Outcome results
None listed