Catheter-Related Infections
Conditions
Keywords
Bandages, Central Venous Catheters, Catheter-Related Infections
Brief summary
The purpose of this study is to compare the use of chlorhexidine-gel-impregnated dressing and the transparent polyurethane film dressing as coverage of the site of insertion of central venous catheter, in the evaluation of catheter colonization in critically ill adults patients.
Interventions
DEVICEchlorhexidine-gel-impregnated dressing
Chlorhexidine Patients receive a chlorhexidine-gel-impregnated dressing ( 3M Tegaderm CHG IV securement dressing™ ) after insertion of central venous catheter
DEVICEPolyurethane film dressing
Polyurethane film dressing Patients receive a transparent polyurethane film dressing (3M Tegaderm IV dressing™) after insertion of central venous catheter.
Sponsors
University of Sao Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Critically ill patients hospitalized carrying a short-term central venous catheter
Exclusion criteria
* Use of a central venous catheter with antimicrobial coating * Suspected or confirmed bacterial infection at randomization * Known allergic/hypersensitivity reaction to any compounds of the treatment * Active lesions in the skin where the CVC is located and / or where the dressing of CVC is being conducted;
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Catheter Colonization | Participants will be followed from placement until the withdraw of the central venous catheter, an expected average of 3 weeks. | With aseptic technique, the central venous catheter will be withdrawn and a 5 centimeters distal portion of the catheter will be cut and conditioned in sterile test tube and sent to the microbiology laboratory. It will be considered a Catheter Colonization a significant growth of one or more microorganism in a semiquantitative culture of the catheter tip. It is according to the Clinical Practice Guidelines for the Diagnosis and management of Intravascular Catheter- Related Infection: 2009 Update by the Infectious Diseases Society of America |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Clinical Exit Site Infection | Participants will be followed from placement until the withdraw of central venous catheter, an expected average of 3 weeks | Erythema, induration, and/or tenderness within 2 cm of the catheter exit site, according to Clinical Practice Guidelines for the diagnosis and management of intravascular Catheter-Related Infection: 2009 Update by the infectious diseases Society of America. |
| Microbiological Exit site Infection | Participants will be followed from placement until the withdraw of central venous catheter, an expected average of 3 weeks | With aseptic technique, a swab will be collected before removal of central venous catheter, the swab will be moistened with sterile saline and rolled for about 2 cm around the exit site. The material will be conditioned in sterile test tube and sent to the microbiology laboratory. It will be considered a Microbiological Exit Site Infection the exudate at catheter exit site yields a microorganism. According to Clinical Practice Guideline for Diagnosis and Management of intravascular Catheter-Related Infection: 2009 Update by the Infectious Diseases Society of America |
Countries
Brazil
Outcome results
None listed