Technique And Results In Endothelial Keratoplasty

Technique And Results Evaluation In Endothelial Keratoplasty

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02470793

Acronym

TREK

Enrollment

Registered

2015-06-12

Start date

2014-09-30

Completion date

2021-01-31

Last updated

2021-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corneal Endothelial Cell Loss, Fuchs' Endothelial Dystrophy

Keywords

Corneal Endothelial Cell Loss, Fuchs' Endothelial Dystrophy, Lamellar Keratoplasty, Descemet Stripping Endothelial Keratoplasty, Descemet Membrane Endothelial Keratoplasty, Minimal Surgical Procedure

Brief summary

To assess and compare the complications and results of different lamellar endothelial keratoplasty techniques and its variations.

Interventions

PROCEDUREDescemet Stripping Automated Endothelial Keratoplasty

Descemet Stripping Automated Endothelial Keratoplasty

PROCEDUREDescemet Membrane Endothelial Keratoplasty

Descemet Membrane Endothelial Keratoplasty

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Diagnosis with corneal endothelial dysfunction requiring lamellar endothelial corneal transplantation. 2. Free acceptance to be enrolled in the trial, and signature of the informed consent by the subject and/or its legal representatives.

Exclusion criteria

N/A

Design outcomes

Primary

Measure	Time frame
Visual acuity	First six months postoperatively

Secondary

Measure	Time frame
Intraoperative complications	First six months postoperatively
Postoperative complications	First six months postoperatively
Endothelial cell density	First six months postoperatively

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026