Advanced Cancer, Cancer, Tumor
Conditions
Keywords
genetic sequencing, genome, cancer, DNA, RNA, protein, metabolite
Brief summary
The primary aim of this study is to identify drivers of cancer by performing comprehensive genetic, proteomic, and metabolomic characterization of patient samples as a basis for understanding the underlying cause of disease.
Detailed description
This study involves looking at the DNA, RNA, proteins, and metabolites in blood and tissue samples collected from subjects and linking them to their health information. By doing so, researchers hope to discover the underlying molecular causes of human diseases with the hope that this information can be used for the development of diagnostic tests and more effective treatments.
Interventions
GENETICMolecular profile
Patients and their treating physician will obtain the patient's genetic risk assessment
Sponsors
Avera McKennan Hospital & University Health Center
Study design
Observational model
OTHER
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients diagnoses with cancer but healthy enough to undergo a biopsy procedure * Between the ages of 18 and 100
Exclusion criteria
* Patients who are pregnant
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Genetic profiling | Up to 15 years | To determine genetic changes associated with the development and growth of human disease. This should lead to better ways to detect, prevent, and treat a wide variety of human health conditions, including cancer. |
Countries
United States
Outcome results
None listed