Desflurane in Children With Laryngeal Mask Airway

Sevoflurane Vs. Sevoflurane-desflurane Anesthesia in Children With Laryngeal Mask Airways; Difference in Respiratory Event, Recovery Time and Emergence Agitation

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02470442

Enrollment

200

Registered

2015-06-12

Start date

2015-06-30

Completion date

2016-03-31

Last updated

2017-08-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Desflurane Anesthesia

Brief summary

The purpose of this study is to characterize the airway responses to desflurane during maintenance of and emergence from anesthesia in children whose airways were supported with laryngeal mask airways (LMAs).

Interventions

DRUGSevoflurane/Desflurane

Anesthesia induced with sevoflurane and anesthetic maintenance with desflurane

DRUGSevoflurane

Anesthesia induced with sevoflurane and anesthetic maintenance with sevoflurane

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

2 Years to 6 Years

Healthy volunteers

Inclusion criteria

* scheduled for elective surgery under general anesthesia with laryngeal mask airway

Exclusion criteria

* history of reactive airways disease with an acute exacerbation within the past 2 weeks * if wheezing or an active upper respiratory infection was present on the day of surgery * if there was a history of malignant hyperthermia * a history of moderate-to-severe hepatic dysfunction following anesthesia with desflurane not otherwise explained.

Design outcomes

Primary

Measure	Time frame
respiratory adverse events	participants will be followed for postoperative period, an expected average of 30 minutes.

Secondary

Measure	Time frame
emergence agitation	15 minutes after arrival on PACU

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026