Heartburn in Pregnancy
Conditions
Brief summary
This study evaluates the efficacy of alginate-based reflux suppressant and magnesium-aluminium antacid gel for treatment of heartburn in pregnancy. Half of the participants will receive alginate-based reflux suppressant, while the other half will receive magnesium-aluminium antacid gel.
Interventions
DRUGAlginate-based reflux suppressant
DRUGmagnesium-aluminium antacid gel
Sponsors
Chulalongkorn University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Pregnant women gestational age less than 36 weeks with heartburn
Exclusion criteria
* Having medical disease that contraindicated to use study drug * Allergic to alginate-based reflux suppressant and magnesium-aluminium antacid gel
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of heartburn as measured by diary chart | 2 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Intensity of hearburn as measured by visual analog scale | 2 weeks |
| satisfaction as measured by questionnaire | 2 weeks |
| quality of life as measured by questionnaire SF-8 | 2 weeks |
| Number of participants with side effects | 2 weeks |
| fetal outcomes as measured by birth weight and Apgar scores | at birth |
Countries
Thailand
Outcome results
None listed