Multiple Pulmonary Nodules, Pulmonary Emphysema
Conditions
Brief summary
To investigate the diagnostic value of ultralow-dose computed tomography in the detection of pulmonary nodules and lung parenchym alterations (e.g. emphysema) compared to standard-dose-CT.
Interventions
RADIATIONUltralow-Dose-CT
Patients undergoing thoracic normal dose-CT with undergo an additional Ultralow-Dose-CT
Sponsors
Cantonal Hospital of St. Gallen
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* planned normal dose-CT by clinical indication at our institution * obtained informed consent
Exclusion criteria
* planned lowdose-CT by clinical indication at institution * no informed consent obtained * age \< 18 years * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of pulmonary Nodules detected in the Ultralow-Dose thoracic CT | Participants CT-scan will be read out on an average date of 6 weeks after the scan | Difference in nodule detectability in Ultralow-Dose-CT compared to Standard-Dose-CT measured using McNemar test |
Secondary
| Measure | Time frame |
|---|---|
| Patients BMI (Body mass index) | Measures assessed at time of read-out on an average date of 6 weeks after the scan |
| Patients Nodule size (mm) | Measures assessed at time of read-out on an average date of 6 weeks after the scan |
Countries
Switzerland
Contacts
Primary ContactMichael A Messerli, MD
Outcome results
None listed