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Early Clinical, Laboratory and Microbiological Predictors of Treatment Outcomes in Infective Endocaridtis

Early Clinical, Laboratory and Microbiological Predictors of Treatment Outcomes Among Infective Endocaridtis Patients in a Tertiary-care Centre in Kerala

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02466139
Acronym
CRP-IE
Enrollment
102
Registered
2015-06-09
Start date
2012-04-30
Completion date
2015-04-30
Last updated
2015-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infective Endocarditis

Keywords

microbiology, c reactive protein, urgent cardiac surgery

Brief summary

The investigators conduct a prospective observational study on consecutive patients being admitted to a tertiary care-centre with infective endocarditis. The investigators' primary aim is to identify baseline clincal, laboratory and microbiological predictors of in-hospital events, mortality and 6-month mortality.

Detailed description

Mortality and major complications among infective endocarditis remain high. In addition developing nations are crippled with a high incidence of culture-negative endocarditis and lack of wide availability of transesophageal echocardiography. We intended to identify predictors among admission clinical features, laboratory paramters and culture reports that can help risk stratify patients early in the course of treatment.

Interventions

None listed

Sponsors

Government Medical College, Kozhikode
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Fulfillment of modified Duke criteria

Exclusion criteria

* No consent * inadequate baseline data

Design outcomes

Primary

MeasureTime frame
In-hospital mortality30 days
Major complications30 days

Secondary

MeasureTime frame
Number of patients who had embolic events30 days
Number of patients who needed urgent cardiac surgery30 days
Short term Mortality6 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026