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To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.

To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.

Status
Withdrawn
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02465619
Enrollment
0
Registered
2015-06-08
Start date
Unknown
Completion date
2017-06-30
Last updated
2017-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cirrhosis

Brief summary

The study will be conducted on patients admitted to Department of Hepatology from MARCH 2015 to DECEMBER 2016 at ILBS, New Delhi.All patients presenting to ILBS fulfilling the inclusion criteria will be included in the study and will be categorized and evaluated. The patient will followed over a period of 3 months.

Interventions

None listed

Sponsors

Institute of Liver and Biliary Sciences, India
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* All consecutive patients presenting to hospital with bilirubin ≥5 and INR≥1.5 * Cirrhosis with or without Decompensation presenting with acute deterioration in less than 3 month

Exclusion criteria

* Cirrhosis with chronic decompensation. * Patient on anticoagulant * Hepatocellular carcinoma * Septic shock * Post-liver transplant or resection

Design outcomes

Primary

MeasureTime frame
Survival28 days

Secondary

MeasureTime frame
total number of patients underwent Transplantation3 months
Mortality3 months
Survival3 months
Number of patients develop SIRS (Systemic Inflammatory Response Syndrome).3 months
Number of patients develop sepsis.3 months
Number of patients develop liver failure.3 months

Countries

India

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026