The Role of Vitamin D3 and Calcium Supplementation in Attenuating T2DM Severity

The Role of Vitamin D and Calcium Supplementation in the Pathogenesis of Type 2 Diabetes Mellitus

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02464462

Enrollment

Registered

2015-06-08

Start date

2010-05-31

Completion date

2013-12-31

Last updated

2015-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes Mellitus

Keywords

serum calcidiol, T2DM, vitamin D3 supplementation, post-menopausal women, ethnic diverse, calcium supplementation

Brief summary

The purpose of this study is to investigate the effect of vitamin D3 and calcium supplementation in attenuating type 2 diabetes mellitus outcomes in ethnic diverse, diabetic patiens.

Detailed description

Subjects of this study received a total of 1800 IU vitamin D3 and 720 mg of calcium per day for 3 years. The study was conducted in Toronto, Ontario, Canada.

Interventions

DIETARY_SUPPLEMENTvitamin D3 and calcium

1800 IU vitamin D3 plus 720 mg Calcium

OTHERPlacebo

Rice powder pills

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

40 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Type 2 diabetes mellitus * Non-white, post menopausal female * Have access to Community Health Center

Exclusion criteria

* neurodegenerative disease * kideny disease * gluten allergy

Design outcomes

Primary

Measure	Time frame
Serum calcidiol	3 years

Secondary

Measure	Time frame
Fasting insulin	3 years
Parathyroid Hormone	3 years
Fasting blood glucose	3 years
Glycated Hemoglobin	3 years

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026