Use of CBCT-based Tooth Replica in Tooth Autotransplantation to Improve the Outcome of Tooth Replacement in Children

Use of Stereolithographic Model in Tooth Autotransplantation and Periodontal Ligament Stem Cells for Pulp Revascularization and Reinnervation to Increase the Success Rate for Tooth Replacement in Children

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02464202

Enrollment

100

Registered

2015-06-08

Start date

2013-05-31

Completion date

2017-12-31

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Increase Success Rate of Tooth Transplantation

Keywords

Tooth autotransplantation, stereolithography tooth replica, CBCT, Outcome

Brief summary

The aim of this study lies in comparing the outcome of the proposed technique in a large sample size group to the outcome of the conventional tooth autotransplantation method and to provide sufficient evidence for improving the long-term success rate of the tooth autotransplantation procedure.

Interventions

OTHERstereolithography tooth replica

Tooth replica will be made and used for preparing the receiving tooth socket during autotransplantation

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

9 Years to 18 Years

Healthy volunteers

Yes

Inclusion criteria

The subjects will be divided in two groups according to different surgical protocols. 1. Pediatric subjects (age between 9-18 years) treated with the CBCT-based replica procedure (prospective approach). Pediatric subjects (N=50) that missed their teeth due to agenesis or lost their permanent teeth due to trauma, caries, and endodontic failure and referred to dentistry department for replacement of the missing tooth by means of tooth autotransplantation. 2. Pediatric subjects (age between 9-18 years) treated with the conventional method (prospective and retrospective). Pediatric subjects (N=50) that missed their teeth due to agenesis or lost their permanent teeth due to trauma, caries, and endodontic failure and referred to dentistry department for replacement of the missing tooth by means of tooth autotransplantation. A matched control patient will be selected with the focus on a very similar surgical challenge, based on age, gender and a matching donor tooth with the same stage of root development and host bed.

Exclusion criteria

* Potential participants (case and control) will be excluded if follow-up data are missing for the one-year follow-up.

Design outcomes

Primary

Measure	Time frame
success rate	5 years
survival rate	5 years

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 22, 2026